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Journal of Ethnopharmacology
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Chu J, Gallos I, Tobias A, et al
If pain persists despite technique adjustments, the issue may be localized tissue sensitivity rather than injection mechanics
Soon after stimulation by an appropriate triggere.g., chemokines/cytokines, pathogen components like lipopolysaccharide (LPS), and/or wounded tissueneutrophils migrate to areas of injury and/or infection and mount an initial innate immune response which requires a rapid metabolic switch dependent on G6PD
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