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In a single piece, he concisely captures: the state of the field the most important clinical trials where the pipeline is headed These Clinical trials are raising the bar and expanding future treatment options: Retatrutide ~24% weight loss (triple agonist) MariTide 1216% weight loss (GLP-1 + GIP antagonist) CagriSema up to 20% weight loss + ~2% HbA1c drop Orforglipron oral GLP-1, HbA1c 1.5%, weight 7.6% IcoSema weekly semaglutide + once-weekly insulin Even more exciting
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High costs and insurance barriers have pushed patients and physicians to seek alternative paths to these medications
NovoCare : Eating Help for patients who are creating a plan for healthy eating, with articles, tips, and diabetes-friendly recipes
Bhardwaj, P., Iyengar, N
Improvements were also seen in all other weight-related parameters, cardiovascular risk factors and glucose metabolism. The trial took place at 37 sites in multiple countries from October 2019 through March 2022
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