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This is one of the few direct comparisons in this encyclopedia where the clinical evidence produces a clear recommendation rather than a balanced assessment of trade-offs

Also, if you have chronic conditions like diabetes or neurological disorders, B12 shots might be part of your treatment

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Documented information about vitamin B12 shot costs and benefits explains why the injection route is often chosen over oral supplements for people with absorption issues or higher baseline needs

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The difference between those who do and those who don't almost always comes down to one variable: whether they're injecting fasted and maintaining a caloric deficit