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Long-term follow-up data from cardiovascular outcomes trials indicate that any early increase in retinopathy events tends to plateau over time, and the overall trajectory of retinal health may ultimately be favorable due to sustained improvements in glycemic control

van den Hoek AM, Zondag GCM, Verschuren L, de Ruiter C, Attema J, de Wit EC, Schwerk AMK, Guigas B, Lek S, Rietman A, Strijker R, Kleemann R.

They have to be injected under the skin once a week

The intensity and duration vary considerably between individuals

First, we lack large-scale, long-term studies proving its beneficial effects on humans