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For instance, in diabetic cardiomyopathy, GLP-1 improves mitochondrial function via Drp1-related mechanism [22]

Fat cells release inflammatory mediators known as adipokines , including: Leptin Adiponectin Interleukin-6 Tumor necrosis factor-alpha These mediators contribute to: Cartilage degradation Synovial inflammation Osteophyte formation Because of these mechanisms, obesity is considered one of the most important modifiable risk factors for knee osteoarthritis

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Carnitine has also been praised for its ability to enhance recovery, in part, due to its ability to stimulate the body's response to insulin which replenishes cellular glycogen