Talchai C, et al
The comparatively higher sample size addresses biological variability, possible attrition and death rates (e.g., Doxorubicin toxicity), and type I error inflation in pairwise comparisons (Tukeys post-hoc test)
A second study investigated delivery of GLP-1 in a SOD1 G93A mouse model using an intracerebroventricular injection of mesenchymal stem cells (MSC) stably transfected to secrete GLP-1 21
This level of weight loss is clinically meaningful and associated with improvements in metabolic health
Greening DW, Xu R, Ji H, Tauro BJ, Simpson RJ (2015) A protocol for exosome isolation and characterization: evaluation of Ultracentrifugation, Density-Gradient Separation, and immunoaffinity capture methods
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