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Mechanistic and preclinical studies show GLP1based therapies enhancing DNA repair, modulating nutrientsensing pathways, and improving mitochondrial quality control, all of which sit at the core of how modern geroscience defines slower aging

West Indian Med J

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A multi-center phase-II clinical trial, started a few years ago to investigate the biological and clinical effects of rapamycin in people with ALS, is currently underway and will provide important information for further potential trials [312], thus opening new therapeutic perspectives for ALS

This period sees the combined effects of inflammation reduction and early tissue repair