21 Heriditary cystatin C amyloid angiopathy (HCCAA): Hereditary cystatin C amyloid angiopathy (HCCAA) is a rare dominantly inherited disease caused by a leucine to glutamine variant of human cystatin C (hCC)
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When to increase dose Consider increasing if: Minimal response after 4-6 weeks at current dose No side effects at current dose Current dose below the higher end of recommended range Goals not being met with conservative approach Increase gradually, typically by 25-50% at a time