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Signal Transduct Target Ther 9:124
The dual-receptor approach may create a more balanced physiological response that reduces acute GI disruption
In rodent models , this mechanism has demonstrated increased pulsatile GH secretion and enhanced endocrine signaling
The difference likely reflects the younger, healthier general obesity population versus TRIUMPH-4's older osteoarthritis cohort
Furthermore, BPC-157 has shown effectiveness in speeding up the recovery from transected muscle injuries and muscle-crushing injuries in rats
It is also contraindicated with multiple endocrine neoplasia syndrome type 2
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