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The DNA sequence encoding cleaved peptides could be identified by high-throughput sequencing of library members in surviving bacteria to quantify the relative activity of the protease on all substrates in the library via high-throughput sequencing

The study also showed that AC partially controls the expression levels of MAPK1, MAPK8, and MAPK14 to provide neuroprotective effects in PD models

One example of such GPCR is the protease-activated receptor 2 (PAR2), which is specifically expressed in the plasma membrane of endometrium epithelial cells and modulates intracellular calcium levels upon activation by serine proteases like trypsin

In the regeneration stage, the fibroblasts (the cells that build the fibers of the connective tissues) proliferate and produce collagens and glycoproteins to form the new tissues

Heurteaux, and M

Cancers (Basel) (2020) 12(2):448