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Gray bar: Normal, untreated mice Yellow bar: Mice receiving antibiotics Blue bar: Mice receiving NMN Red bar: Mice receiving antibiotics and NMN The yellow and red bars represent mice given antibiotics to deplete their gut bacteria
Skin is alive
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Markus V, Share O, Shagan M, et al
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At such levels, even a 500mcg dose requires only 0.05mL
In turn, reperfusion initiates a cascade of free radicals that result in apoptosis by inducing mitochondrial damage, cytochrome-C (Cyt-C) release, and activation of multiple pathways
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