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In the present study, disrupted hepatic glutathione homeostasis was observed in mice chronically exposed to a HFD diet, which is characterized by GSH reduction and GSSG elevation
Multiple syndromes of 3-methylglutaconic aciduria Pediatr Neurol
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GSH can also be oxidized to its disulfide form (GSSG) by reactive oxygen species (ROS) and other electrophiles, which can be reduced back to GSH by GR using NADPH as a reducing agent
D.MazurM.TelserJ
Plant J 36(5):602615
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