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Well focus on the gut, our immune system and the brain, or more simply whats called the Gut-Immune-Brain axis
This is the primary clinical rationale for IV administration when therapeutic-level replenishment is the goal
However, the natural role of the body's own brief burst of GLP-1 (a hormone made in the gut) has been hard to understand, mainly because it gets broken down so quickly that it barely reaches the pancreas
Cell 160 , 805806 (2015)
Cell Metab (2020) 31(2):267+
Universally, participants were willing to tolerate these side effects for improvements in physical health including their weight
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