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Clostridium butyricum makes butyrate, a shortchain fatty acid that signals GLP-1secreting Lcells
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In Vitro 18, 231243 (2004)
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Critically, research by Leal-Cerro and colleagues confirmed that endogenous GHRH is required for most of the GH response to GHRP-6, demonstrating that GHRPs work synergistically with the hypothalamic GHRH system rather than independently from it
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