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Microvascular and cardiovascular outcomes according to renal function in patients treated with once-weekly exenatide: insights from the EXSCEL Trial
Substitution with Tyr 13 scarcely affects the activity of GIP (114) analogues, 33 implying that the use of Tyr 13 in the designed dual agonist may not conspicuously affect GIP activity
The degree to which a secretagogue raises only GH, versus also nudging ACTH/cortisol and prolactin, is a central axis on which these compounds are compared
The likely reason is a combination of reduced inflammation, better blood sugar control, and improved vascular health
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