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It is also the one most likely to make you question whether the supplement is working or making things worse
Pharmacological Research 95 , 111-125 (2015)
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On either pill the frequent reactions are gastrointestinal: nausea, vomiting, and diarrhea, along with constipation, abdominal pain, indigestion, bloating, belching and gas, and reflux or heartburn
Antidepressants like duloxetine or amitriptyline may be considered after discussion of potential benefits and harms
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