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The compound's interaction with VEGFR2 triggers rapid autophosphorylation of tyrosine residues 1175 and 1214, essential for subsequent recruitment of adaptor proteins including Grb2 and Shc
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Mabalirajan U, Ahmad T, Leishangthem GD, Dinda AK, Agrawal A, Ghosh B
The rate of weight loss tends to be higher in the initial months as the body adjusts to the medication and the effects on appetite and metabolism take hold
Yang M, Chen P, Liu J, Zhu S, Kroemer G, Klionsky DJ, et al
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