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Longitudinal studies and clinical trials will be necessary in the future to determine the validity of biomarker cut-off thresholds, standardization of methods for sample collections, and to assess the incremental predictive value of these markers in large, diverse populations
Butler T
,
Oxygen radicals that may initiate lipid peroxidation, leading to ferroptosis, include the hydroperoxyl radical (the conjugate acid of superoxide) and the hydroxyl radical, which itself can be formed from the Fenton reaction between hydrogen peroxide and iron
S., Elgendy, M
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