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Compound 4 demonstrated comparable potency to 3 (EC 50 = 4.6 M
In contrast, impaired tissue glucose uptake in response to insulin (a phenomenon called insulin resistance) plays a key role in the development of type 2 diabetes (55)
Overall, findings demonstrate that ALC is comparable to MC, the current medication recommended by Chinese guidelines for the treatment of diabetes, in improving DPN symptoms
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Effect of the vehicle in the bioassay of hCG [PMID: 4098627] Laboratory literature summary: Effect of the vehicle in the bioassay of hCG
Calcium-mediated cell death during myocardial reperfusion
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