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This receptor interaction activates intracellular signaling pathways, primarily via adenylate cyclase stimulation and increased cyclic AMP (cAMP) production

doi: 10.4162/nrp.2011.5.4.357 Rayman MP

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Research has examined its role in the relevant signalling pathways and cellular models in vitro

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The peptide also modulates the nitric oxide (NO) system, which may explain its observed effects on blood pressure regulation and vascular healing in rat models 8