Jr., Ulm, M
doi: 10.1016/j.ejbt.2022.11.003 55 CuiX.MaoP.SunS.HuangR.FanY.LiY.et al
FidanzaAToschiPZacchiniFCzernikMPalmieriCScapoloPet al
Outcome measures include neurological severity scoring, rotarod and beam walk performance, histological assessment of lesion volume, and immunohistochemistry for axonal markers and myelin basic protein
What the other five PCAC peptides look like The committee will hear seven peptides over two days
Frederick et al., 2016), reduces the mitochondrial unfolded protein response (Mendelsohn and Larrick, 2017), disrupts ATP biosynthesis, decreases the ability to pump calcium against the intracellular gradient (Camandola and Mattson, 2011), disrupts calcium homeostasis, increases excitotoxicity (Rzheshevsky, 2014) and has deleterious effects on muscle health (Goody and Henry, 2018)