First, leptin is taken up by tanycytic end feet adjacent to ME capillaries and is transported into the CSF of the third ventricle in a leptin receptor-dependent manner [123, 124]
Li Y, Sun W, Han S, Li J, Ding S, Wang W, Yin Y (2016) IGF-1-involved negative feedback of NR2B NMDA subunits protects cultured hippocampal neurons against NMDA-induced excitotoxicity
0.4% with placebo and 1.1% with dulaglutide [24]
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