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DOI: Published online: October 15, 2025 1 Diabetes Care Center, Jinnouchi Hospital, Kumamoto, Japan 2 Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan 3 Kurinami Clinic, Kanzaki, Kumamoto, Japan 4 Division of Cardiovascular Medicine, Diabetes Care Center, Jinnouchi Hospital, Kumamoto, Japan 5 Division of Preventive Cardiology, Department of Cardiovascular Medicine, Kumamoto University Hospital, Kumamoto, Japan Corresponding author: Hideaki Jinnouchi

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And when I assess, and I'm sure you do the same, like we don't use conventional testing

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Phase Reta escalation 1 Weeks 5-8 Retatrutide 4 mg/week Cagrilintide Not started Notes Continue retatrutide alone