For mTYR, the narrow dual copper-binding site makes it more difficult for arbutin, which has two rings, to fit, especially in the MD-stable conformation of Arbutin_b, where the number of hydrogen bonds between arbutin and the pocket is much lower than in other conformations (Table 2)
The GHK peptide sequence occurs naturally
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Thats one reason why the anecdotes we read on social media should be taken with a mountain of salt
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