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The authors noted that well-designed, adequately powered clinical trials were lacking, and that definitive efficacy claims could not be supported by the existing literature at the time of publication

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Clinical studies have shown that a combination of glycine and N-acetylcysteine reliably increases low glutathione levels and thus reduces oxidative stress

The study also indicates a progressive trend, with Wegovy, recognized as the most potent GLP-1 RA, administered at the highest dose and renowned for its remarkable reduction in body weight

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