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Insurance Coverage Note Many direct-to-consumer prescription products are not covered by traditional insurance plans, but coverage policies vary

It is currently indicated for use in adults with obesity (with a BMI of 30 kg/m2 or greater) or overweight adults (with a BMI of 27 kg/m2 or greater) who also have weight-related medical problems such as type 2 diabetes, high blood pressure, obstructive sleep apnea, or cardiovascular disease

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The dose for weight loss is usually lower than the dose used for diabetes management

2 studies scored seven, indicating medium-quality studies with low risk of bias

The primary outcome is the change from baseline as measured by the Edmonton Symptom Assessment Scale total symptom distress score at Day 14