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They are associated with an abnormal EEG pattern called hypsarrhythmia and, when untreated, carry a poor developmental prognosis. Any infant showing sudden, repetitive flexion or extension movements occurring in clusters, particularly on waking, should be assessed urgently
de Figueiredo SM1 (1) Universidade Federal de Ouro Preto, Ouro Preto, MG, Brasil
The tests are simple to administer and take and are widely available
J.VerschuureP.KappG.KingS
In skeletal muscle, IGF-1 LR3 activates satellite cells, promoting their proliferation and differentiation into mature muscle fibersa process termed hyperplasia (increase in cell number) distinct from hypertrophy (increase in cell size)
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