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Moreover, knockdown of PKC using an antisense oligonucleotide (ASO) protected rats from fat-induced hepatic insulin resistance [109], and PKC knockout mice ( Prkce ) mice showed improved glucose tolerance than wild type controls after 7 days of high-fat feeding [118]
The treatment is administered to reduce the risk of major cardiovascular events (cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke) in adults with type 2 diabetes who were confirmed with cardiovascular disease
Yaghoubfar et al., 2020), -tocopherol, and -sitosterol (Zhao et al., 2017), positively correlate with A
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