Nausea Vomiting Diarrhea Constipation Decreased appetite Injection-site reactions Gallbladder events (cholelithiasis, cholecystitis) reported in some Phase 2 participants Increased heart rate Possible pancreatitis (per GLP-1 class data not specifically reported in retatrutide trials) Frequently asked questions Is retatrutide FDA-approved
Animals 12, 2145
Mechanisms underlying cardiovascular effects of incretin therapy In addition to glycemic effects, GLP-1RAs also favorably modulate multiple cardiovascular risk factors via acting on a variety of organ systems
Just days ago, Novo Nordisk announced top results from Part 1 of the pivotal Phase 3 trial of ESSENCE
Secondary outcomes related to treatment satisfaction, well-being, and lifestyle
Brian Lee, an associate professor of clinical medicine at the University of Southern California, who serves on the committee, argued as much yesterday