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Declining estrogen levels promote central fat accumulation, insulin resistance, and reduced lean mass

Effects of glucagon-like peptide-1 receptor agonists on liver-related and cardiovascular mortality in patients with type 2 diabetes

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In the first phase 3 trial, people on the 12 mg dose lost around 24% of their body weightroughly 60 poundsover 68 weeks, counting everyone who started the trial, not just the people who stuck with it perfectly

Retrieved 28 February 2026

GLP-1 medications work by mimicking a hormone that regulates blood sugar, slows digestion, and reduces appetite