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Key advantage: Works even when Viagra/Cialis fail No interaction with alcohol or food Effective in neurogenic, psychogenic, and post-surgical ED Indications Erectile dysfunction (especially PDE-5 non-responders) Low libido (male & female) Performance anxietyassociated ED Adjunct to PDE-5 inhibitors Post-prostate or vascular compromise patients Administration Route : Subcutaneous injection Site : Abdomen or thigh Needle : 31G insulin syringe Timing : On-demand Dosing guidelines Start Low, Titrate Up Men Starting dose: 0.5 mg SQ Typical effective dose: 1.0 mg SQ Max dose: 1.52.0 mg SQ Frequency: No more than 1 dose per 24 hours, 23x per week max Women Starting dose: 0.250.5 mg SQ Typical dose: 0.51.0 mg SQ Onset & duration Onset: 3090 minutes Peak effect: ~24 hours Duration: 612 hours (sometimes longer) Important counseling point:PT-141 increases desire first , erection may follow

Funding This study was done with internal departmental funding from the Department of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network (Toronto, ON, Canada)

4.01.26 MDL numbers increased leading into April The Wegovy MDL had 3,546 pending actions

Additional testing is recommended after significant weight loss (10% or more of body weight), as this may affect your levothyroxine requirements

Injections can be given any day of the week at roughly the same time, with or without meals

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