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This means that fewer nutrients can pass into the bloodstream and that the small intestine is damaged

Cytoplasmic condensation and antibiotic-induced cell death are mitigated by glutathione, a scavenger of reactive metabolic by-products We next sought to determine whether the reactive metabolic by-products that are associated with cytoplasmic condensation also contribute to antibiotic lethality, as measured at the single-cell level by the frequency of condensation and lysis as well as in bulk culture by time-kill assays

doi: 10.1038/s41419-020-2298-2 16 ZhangJDuJKongNZhangGLiuMLiuC

The New England journal of medicine 375 , 311322 (2016)

Studying dose-response on one component while holding the other constant multi-arm protocols with separate vials

B12 supplementation is particularly relevant because GLP-1 agonists can reduce B12 absorption over time