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In the phase 3 ACHIEVE-3 trial , adults with type 2 diabetes inadequately controlled by metformin were randomized to receive orforglipron or oral semaglutide (7 mg and 14 mg, doses approved for type 2 diabetes)
doi:10.1093/jn/130.4.978S
This structure protects patient safety while allowing pharmacists to prepare individualized dosing strengths and formulations that may not be commercially available in standardized form
The results are summarized in Table 2
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