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While GLP-1s are generally well tolerated and offer numerous health benefits from weight loss and better glucose control to a lower risk of cardiovascular disease research suggests they could increase the risk of certain serious eye conditions
Tirzepatide for Weight-Loss Maintenance May 2026 SURMOUNT-MAINTAIN evaluated continuing, reducing, or stopping Zepbound after initial weight loss The issue: Patients who reach their weight-loss goal on Zepbound often ask what maintenance therapy should look like
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Patients should start by choosing smaller portions or appetizer-sized servings, as the delayed gastric emptying caused by GLP-1 drugs means less food is needed to achieve fullness
This increase in visceral fat the fat stored around internal organs is linked to higher risks of heart disease, stroke, and other health problems
Some people experience severe abdominal pain
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