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Silymarin has been associated with GI discomfort in some individuals, including cramping, flatus, nausea, vomiting, diarrhea or dyspepsia
Additionally, pretibial myxedema occurs Due to dermal fibroblast stimulation that leads to GAGs deposition in the connective tissue
Chemically induced mutagenesis and carcinogenesis often begin with the formation of DNA adducts 7
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Since stress-responsive cis -acting elements existed in the promoters of the RcGPXs , qRT-PCR was performed to investigate the expression change of RcGPXs under cold, drought, and salt stresses (Figure 4)
