is weight watchers using semaglutide What will do with compounded GLP-1s after May? Is anyone doing Semaglutide with

The two peptides differ on every axis that matters for protocol design: origin, structural class, mechanism, the repair-cascade window they appear to act on, and the strength of the underlying evidence

GIP PHYSIOLOGY: SIMILARITIES AND DIFFERENCES WITH GLP-1 GIP is a 42-amino acid peptide secreted from intestinal K cells that are located mainly in the proximal small intestine

The initial weight loss with semaglutide may be modest, often due to fluid shifts and appetite changes

12 Furthermore, postmarketing reports of acute pancreatitis, both fatal and nonfatal hemorrhagic and necrotizing, and rare hypersensitivity reactions such as angioedema and Stevens-Johnson syndrome may limit use in certain populations

PubMed PMID: 27101990

Emerging evidence suggests that GLP1 therapy can: Reduce hepatic fat content, as shown in MRI-PDFF studies Lower markers of liver inflammation and fibrosis Improve insulin sensitivity and metabolic control Although most trials focus on obese or diabetic populations, livercentric endpoints are increasingly evaluated, and benefits appear to extend beyond weight loss alone