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Neuroprotection Research Applications Research applications extend to neuronal protection mechanism investigation: Oxidative Stress Models: Studies on protection against ROS, lipid peroxidation, and oxidative damage Ischemic Injury Research: Investigation in stroke models and oxygen-glucose deprivation Excitotoxicity Studies: Research on glutamate-induced neurotoxicity protection Mitochondrial Function: Investigation of bioenergetics and mitochondrial protection Inflammatory Modulation: Studies examining neuroinflammation and microglial activation Experimental models include primary neuronal cultures under stress conditions, hippocampal slice preparations, and in vivo neurological injury models assessing DSIPs neuroprotective efficacy

10.1210/jc.2016-2007 165 KovameesO.ShemyakinA.ErikssonM.AngelinB.PernowJ