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Being honest about that gap is not a weakness of this guide it is the accurate picture, and it is why every dosing figure here is framed as a research protocol rather than a recommendation

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Look for: One-sided leg pain Swelling Redness Warmth These symptoms can signal a pulmonary embolism and require emergency care: Sudden shortness of breath Chest pain is worse with deep breathing Rapid heart rate Fainting Coughing up blood Quick response improves outcomes and lowers the risk of complications