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GLP-1 therapies slow down the process of food digestion and increase feelings of fullness, leading to a reduction in food intake

Combination therapies that unify the benefits of SGLT2 inhibition with other glucose-lowering mechanisms (like GLP-1 agonism) are also in development to provide multifaceted treatment approaches

The body responds by activating: Reninangiotensinaldosterone system (RAAS) Sympathetic nervous system Cortisol and catecholamine release These hormones are all insulin antagonists they increase hepatic glucose output and reduce glucose uptake

Type 1 predominates in the sebaceous glands and scalp, contributing directly to follicular DHT levels

Researchers tracking comprehensive metabolic outcomes should monitor blood pressure, lipid panels, and inflammatory markers alongside weight when evaluating either compound