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The relative luciferase activities were determined through the Dual-Gloluciferase system (Promega, USA) according to the protocol
Under physiological conditions, cells maintain a highly reduced intracellular environment, reflected in a GSH: GSSG ratio near 100:1 (4-5)
The standard schedule keeps each injection at 2.8 mg: daily in weeks 14, 5x per week in weeks 58, and 2-3x per week in weeks 912
Akt signaling pathway in macrophage activation and M1/M2 polarization
When administered by a qualified medical professional, MIC injections are generally safe
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