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reported that inhibition of the Xc- transport system using sulfasalazine, while ineffective as a monotherapy, was highly effective to eliminate AML cell lines when combined with Buthionine sulfoximine (BSO), an inhibitor of glutamyl cysteine synthetase, the first enzyme in the synthesis of GSH

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81 Combining immunotherapy with conventional treatments can eradicate tumor cells while concomitantly reversing the immunosuppressive tumor microenvironment

), groups III and IV received oral CLO (50 and 100 mg/kg, respectively) in addition to CY (200 mg/kg, i