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Increased concentrations of lipids (cholesterol and triglycerides) in the blood have been correlated to higher serum -tocopherol concentrations
Supplements are considered when needs are higher or intake is limited
179 A study in 43 obese/overweight adults with obstructive sleep apnea found that a supervised exercise program involving 150 minutes per week of moderate-intensity aerobic exercise plus strength training led to reductions in sleep apnea severity, depressive symptoms, and fatigue, and also improved daytime functioning
Bailey CJ, Flatt PR, Conlon JM
Notably excess glutamate has also been implicated in most if not all of the conditions discussed here including ME/CFS indirectly via allostatic load (Goertzel et al, 2006) and the concept of the selfish brain (Peters et al, 2004)