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Not every month but definitely several times a year

Animal-to-human translation is uncertain

10.1016/j.amepre.2010.01.001 Summary Keywords sickle cell disease, hemolysis, heme toxicity, scavenging receptors, transfusion Citation Xue J and Li X-A (2024) Therapeutics for sickle cell disease intravascular hemolysis

Its also worth being careful with expectations: if your B12 levels are already normal, injections are unlikely to be a meaningful energy boost

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