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10.1210/en.2009-0220 Endocrinology 71 WilliamsD
Stronger Side Effects: The rapid delivery of a larger dose can result in more noticeable side effects, such as nausea, diarrhea, and constipation
It is important to stress that insufficient levels of B12 raise susceptibility to infections and diseases, and are very harmful to the nervous system which in turn can cause neurological disorders and severe and sometimes irreversible nerve damage
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Two Phase 3 trials for AD109 with similar design to MARIPOSA are ongoing with topline results anticipated in mid-2025
Open communication is key to a successful transition
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