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In rodents, intracerebroventricular (ICV) administration of the GLP-1R antagonist exendin-9 suppressed the effects of peripheral GLP-1R agonist administration (liraglutide and exenatide) on food intake reduction
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Long-term use is possible with appropriate monitoring
Thus play the role of kidney protection
Retrieved 2 June 2025
In conclusion, the benefits of GLP-1RAs in MASLD are promising, and background therapy involving metabolic modulation may represent one of the future therapeutic paradigms
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