The efficacy of this therapeutic combination was first validated in our breast cancer models, demonstrating that PHGDH wild type breast cancer cells do not respond to the therapeutic combination, whereas PHGDH-amplified breast cancer cells exhibited a synergistic sensitivity to suboptimal dosages of sertraline plus chloroquine (Figure S8A)
Hu Y, Wang C, Wang H et al (2023) Global transcriptomic analysis reveals PhoPQ-mediated multi-drug resistance networks in Acinetobacter baumannii
Results: A total of 26 laboratories from 19 countries responded to the survey 8 (42%) were from high income countries and 11(58%) were from low-middle income countries
The presence of NAFLD increases the incidence of type 2 diabetes and accelerates the development of complications in type 2 diabetes [5]
So, antioxidants extra t efonct in biological ssystemswith the help of various mechanisms such as gene expression regulation, co-antioxidants, metal ion chelation, and electron donation (Lobo et al., 2010)
A part of group of compounds called Polyphenols, it acts like an antioxidant and helps protect the body against aging and damage