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doi: 10.1016/j.ejmech.2015.04.040 30 GuoCSunLChenXZhangD

Finally, selenium deficiency is associated with cardiovascular disease and cancer, leading to an increased burden of comorbidities in patients with kidney disease

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It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine

The development of intrarenal crystals can result in tubular obstruction, direct toxic injury to the renal tubular epithelium, and reduced perfusion due to vasoconstriction of the afferent arterioles, thus fostering the occurrence of AKI