Authoritative Sources The New England Journal of Medicine phase 2 trial reports retatrutide efficacy and adverse-event findings in obesity research
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more than 50% of patients also reported that improved sleep was the most significant lifestyle improvement they noted from losing weight
Estimated fat mass fell by 9.9 lbs (4.5 kg) in the treatment group versus 1.5 lbs (0.7 kg) in placebo, and estimated visceral fat area dropped by 5.04 in (32.5 cm) versus 1.39 in (9.1 cm) [4]
In studies with rodents, semaglutide caused thyroid tumors, including thyroid cancer