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This linear relationship makes the math predictable once you understand the underlying formula, and you can find similar breakdowns for other unit amounts in our complete tirzepatide conversion chart

In head-to-head clinical trials, tirzepatide produced greater average weight loss than semaglutide at comparable endpoints

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Those with severe renal impairment, uncontrolled hypertension, or active psychiatric conditions involving appetite regulation should discuss risks and benefits with their provider before initiating therapy