One explanation could be the susceptibility of the mice to MTB infection and/or the high dose of aerosol MTB used in our challenge, as evidenced by the CFU count of ~10 7 CFU in the nave group
the dose range is derived from the individual compounds
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Choline : Choline is an essential amino acid that is used throughout the body to build cell membranes, maintain healthy muscle and liver function, and produce acetylcholine, a neurotransmitter that regulates mood and is involved in forming memories and controlling muscle contractions
It facilitates cell migration to injury sites, promotes cell differentiation, supports actin-mediated tissue remodeling, and reduces scar tissue formation